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Azelastina (Azelastine)
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Azelastine

Azelastina is unique among antihistamines presently available in the USA because it is administered by nasal spray. After intranasal administration, its systemic bioavailability is approximately 40%. Azelastina has an onset of action within the first hour of administration and reaches peak activity at 1–3 hours after administration. Duration of activity is about 12 hours. Intranasal administration results in maximal plasma concentrations in 2–3 hours. Azelastina has an active metabolite, desmethylAzelastina, which probably extends the duration of action of the drug. The half-life of the parent compound is 22 hours and that of the active metabolite 54 hours. Ten days after oral administration of 4 mg radiolabeled Azelastina, approximately 24% of the radioactivity was recovered in the urine and 75% in the feces.

Other names for this medication:
Azelastine, Afluon, Allergodil, Astelin, Astepro, Asthafen, Azel, Azelastin, Azelastina, Azelone, Azen, Azep, Azeptin, Ketasma, Lastin, Optilast, Optivar, Otrivine, Phenergan, Rhinolast, Rinalin, Xanaes,

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Azelastina is used to relieve nasal symptoms such as runny/itching/stuffy nose, sneezing, and post-nasal drip caused by seasonal allergies and other allergic conditions. This medication is an antihistamine. It works by blocking certain natural substances called histamines that are responsible for allergic symptoms.

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regarding cost-utility analysis of dengue vaccination in a country with heterogeneous risk of dengue transmission. AnxA5 is present at the surface of these vesicles and may thus participate in plugging the cell membrane disruption.

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Because the prodomain of TGFbeta interacts with latent TGFbeta-binding proteins, a family of molecules homologous to the fibrillins, the prodomain of BMP-7 was tested for binding to fibrillin-1 or to LTBP-1. This study describes the clinical presentation of RP, the prevalence of associated treatable disorders and the characteristics of patients with severe visual impairment and blindness. Therapeutic interventions are discussed that address lack of awareness after ABI. Hemispherectomy in the treatment of pediatric symptomatic epilepsy of children

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Potential biomarkers found by protein profiling may provide insight for the macrovascular pathogenesis of diabetes mellitus. Members of both the Wnt and bone morphogenetic protein (BMP) families of signaling molecules have been implicated in the regulation of cartilage development. Physical activity constitutes a promising strategy to improve cognitive function following stroke. Better understanding of the predictors, causes of deaths, comprehensive rehabilitation, community integration, and regular follow-up could possibly assist in improving survival rates. Enzyme molecules that have been modified by covalent attachment of a benzaldehyde nucleotide derivative in the presence of template DNA are subsequently incubated with radioactively labelled nucleoside triphosphates.

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