Bisoprolol is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

• Tablet

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Useful minimal criteria for an insomnia disorder include persistent nighttime symptoms with daytime distress or impairment. Nonetheless, basal haemodynamic variability may impair BSR accuracy compared with hyperaemic stenosis resistance (HSR). How good is a morning cortisol in predicting an adequate response to intramuscular synacthen stimulation? Consistent with this root hair phenotype, the PM localization of M3 phosphorylation-defective PIN1 and PIN7 was partially disrupted, resulting in less auxin efflux and restoration of root hair growth.

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Our experiments show that with oxygen plasma treatment, the non-adhesive property of the PEG surface deteriorates significantly, leading to non-selective assembly with complete surface coverage of nanocolloidal beads under the same processing condition. A factor mediating interaction of kinins with the genetic material. Effects of fasting on intermediate hepatic metabolism of the rat. To analyze the mobile phone usage and its effectiveness in TB DOTS treatment. Neural mediators of spontaneous physical activity are currently undefined, although the amount of time spent in sedentary positions versus standing and ambulating may be important in the energetics of human obesity.

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Furthermore, mechanisms of immunosuppression in the pancreatic cancer-bearing host were clarified by the identification of myeloid-derived suppressor cells (MDSCs), which also promote disease progression. We describe an unusual case of generalized granuloma annulare (GA) in a 70-year-old man. Captopril prevents myosin light chain phosphatase isoform switching to preserve normal cGMP-mediated vasodilatation.

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Gait analysis has been used as an investigative tool for locomotion disorders since the early 20th century when it was done using time-lapsed photography. The use of desoxycorticosterone acetate (DOCA) in the management of pemphigus. Fast-food consumption, diet quality, and neighborhood exposure to fast food: the multi-ethnic study of atherosclerosis.

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As drugs are one of the few modifiable risk factors for thrombosis, further study and dissemination of knowledge regarding drug-associated and drug-induced thrombosis are essential and have the potential to lead to decreased future incidence of thrombosis. At the testing session, participants completed subjective ratings of mood and ratings of intensity and pleasantness of salt and sucrose solutions, followed by measurement of the threshold at which these solutions could be detected on the tongue. Application of orthogonal functions to spectropolarimetric analysis of some penicillins. At stage XI both the axis-forming and inhibitory capacities of the PM fragment become weaker and an axis-forming capacity starts to build up anterior to the PM, resulting in the formation of two primitive streaks at 90 degrees to each other. Yeast strains were constructed carrying multiple mitochondrial markers conferring resistance to the inhibitors erythromycin, chloramphenicol, paromomycin and oligomycin.

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The treatment of classical hemophilia with factor 8 concentrates. This is a case report of a 52-year-old lady, with systemic mastocytosis, who presented with severe chronic back ache and no other clinical features. Coated vesicles were occasionally found in association with the subplasmalemmal densities.

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A new genetic construct for regulating cytokinin content in plant cells was cloned and tested. Mutations in the tyrosine aminotransferase gene have been identified to cause tyrosinemia type II which is inherited in an autosomal recessive manner. Results of an experimental study of a phthivazid-resistant BCG strain

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One week after removal of the lymph node, only an afferent lymphatic and a deposit of the contrast medium at the popliteal region were observed. In particular at higher angles of incidence, reflectance spectra using p-polarized light are dominated by bands from modes that have their transition moments perpendicular to the surface. The RN-BSNs and their colleagues in Seoul and Busan were subjects. Hypothermia among resort skiers: 19 cases from the Snowy Mountains. Moreover, intriguingly, genetic work on a two-generation pedigree has opened new research pointing to a role for histamine, a so far rather neglected neurotransmitter, with the potential of the development of new treatment options.

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Molecular imaging with surface-enhanced Raman spectroscopy nanoparticle reporters. Coupling between chromosome completion and cell division in Escherichia coli. Role of MRI in the management of children with diffuse pontine tumors: a study of 15 patients and review of the literature. The advances in preparation of cellular monodispersed samples allow the examination not only of in vitro and hematological, but also of surgical, biopsy, endoscopic, and lavage specimens. Pursuant to conserving blood supplies, and based on experience of patients with other causes of iron deficiency anemia, a regimen of high-dose iron supplementation was adopted.

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A tyrosinase nanosensor based on metal-organic frameworks (MOFs) and chitosan was developed to investigate the electrochemical response characteristics and mechanisms of nine kinds of BPs for the first time. It is therefore proposed and discussed that in carrot, similarly to protozoa, TS and DHFR are present on a single bifunctional polypeptide of 58 kDa. These results suggest that classification criteria for mild persistent asthma may need to be re-evaluated.

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These derivatives proved to antagonize the action of gastrin, with ED 50 of between 0.5 and 3 mg/kg. Our findings suggested the risk factors of concomitant BA in AR patients may be helpful to establish preventive strategies. Environmental hypersensitivity: would we really accept the results of sound research? 8th International Conference on Plant Growth Substances held in Tokyo, 8-26--9-1-1973 Little is known about whether buccal mucosa elasticity influences the determination of surgical margins for buccal carcinomas.

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Anti-VEGF therapies have been used successfully in the clinic, encouraging their use in the treatment of other neovascular eye diseases. A tilt angle of 18 degrees was observed in 18:1-O-PC/DOPG (9:1) lipid bilayers, which have a hydrophobic thickness that approximately matches the hydrophobic length of the trans-membrane helix of Vpu. Glycine receptors are pentameric ligand-gated anion channels composed of two different subunits, named alpha und beta, that assemble with a fixed stoichiometric ratio of two alpha to three beta subunits. The study population of this cross-sectional study consisted of 241 patients with SCA or SCD who were admitted to an academic hospital, in Tehran, Iran, from 2011 through 2012.

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Whole-body protein turnover in chicks fed control, histidine, or methionine plus cystine-free diets. Proteinase activity of extracts of human gastric adenocarcinomata. Molecular phylogenetic relationships among seven Japanese species of Cercopithifilaria.

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The classic burn claw hand deformity includes extension contracture of the metacarpophalangeal joints and flexion contractures of the proximal interphalangeal joints. Here, a novel approach was developed based on the quantitative determination of the key intermediate H2O2 produced during accelerated oxidation by ambient oxygen. Brain functions, such as perception, motor control and learning, and decision making, have been explained based on a Bayesian framework, i.e., to decrease the effects of noise inherent in the human nervous system or external environment, our brain integrates sensory and a priori information in a Bayesian optimal manner.

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The long non-coding RNA CCAT2 is up-regulated in ovarian cancer and associated with poor prognosis. A monoclonal antibody against human fibroblasts recognizes a cell surface antigen with increased expression in immortal cell lines.

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To test this model, we monitored the uncatalyzed and enzymatic reactions of dithranol, a substrate for the nogalamycin monooxygenase (NMO) from Streptomyces nogalater As with flavin, dithranol oxidation was faster at a higher pH, although the reaction did not appear to be base-catalyzed. Some statistical implications of dose uncertainty in radiation dose-response analyses. The use of radioisotope-labeled peptides and proteins in bioassays is diminishing as a consequence of the emergence of fluorescent lanthanide-labeled probes.

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To evaluate the effectiveness of unilateral lateral rectus muscle recession and medial rectus muscle resection with or without advancement in treating postoperative consecutive exotropia. The adenovirus early region 4 ORF4 protein (E4orf4) subverts signaling by Src family kinases (SFK) to perturb cellular morphology, membrane traffic, and organellar dynamics and to trigger cell death. These proinflammatory factors induce the expression of secondary mediators such as lipids and reactive oxygen species leading to further amplification of inflammation.

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We found that by incorporating information about classification of proteins and protein sites we are able to detect novel clusters of cancer somatic mutations. Radiation Dose to the Breast by 64-slice CT: Effects of Scanner Model and Study Protocol. Ingrowth of sprouting substance P fibers presumably reflects a nociceptive and maybe a proliferative role, possibly as reactions to repeated microtraumata, whereas the decreased occurrence of tyroxin hydroxylase may represent a reduced antinociceptive role. To study the effect of monoclonal antibody (McAb) against helicobacter pylori (Hp) ureB, 1F11 on platelet aggregation and activation, and its mechanism. Use of tobacco in Latino cultures is most common among men, and most prevalent in social situations.

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Oligonucleotide-based microarray: a new improvement in microarray detection of plant viruses. Urine specimens were tested for CT and NG using a PCR pooling algorithm. In order to understand the nature of these expanding cortical neuronal progenitor cells, we selected by differential display some transcripts that were enriched in the telencephalon as compared to the more caudal regions (diencephalon/mesencephalon).

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Assessing urinary flow rate, creatinine, osmolality and other hydration adjustment methods for urinary biomonitoring using NHANES arsenic, iodine, lead and cadmium data. Sore throat, otalgia, fever, dehydration, uvular edema, and tonsillar hemorrhage are common complications. Phenotypic properties of a large-cell, radiation-resistant strain of Escherichia coli.

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Dose-dependent telenzepine inhibition of the secretion of human gastric acid stimulated by sham feeding and saliva The urgent need for biomedical research into the clinical problems of the elderly. Application of restriction fragment length polymorphism (RFLP) and high resolution melting (HRM) analysis of beta-tubulin gene for species and strains differentiation in Trichophyton mentagrophytes species complex. The role of the epiphyseal and metaphyseal circulations on longitudinal growth in the dog: an experimental study. Rat lung transplantation is a proven experimental technique for the study of lung injury following lung transplantation.

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LC-MS Determination of remifentanil in maternal and neonatal plasma. Frequent neck-shoulder pain is a preceding symptom for the depressive symptomatology in adults. Bladder diverticula often come to clinical attention when complications or malignancy occur, although limited information is available regarding histopathologic features and clinical outcomes.

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Synaptic vesicle proteins must be sorted and concentrated on the plasma membrane, packaged into a budding vesicle of precise size and cut away from the synaptic surface. We found that PEITC induced a selective apoptosis and suppressed tumorigenicity and migration of malignant glioma cells. Consequently, this study aimed to explore the influence of long-term night shift work on the sleep patterns of nurses and their cardiac autonomic nervous system during sleep. In rheumatoid arthritis, synovium is the active site for the interplay between the immune and bone cells, the study of which accelerated the interdisciplinary field of osteoimmunology.

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Research trends of ecotoxicity of nanoparticles in soil environment. Improving detection of hypertension in girls with turner syndrome using ambulatory blood pressure monitoring.

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We were able to identify neurons within the transplant which responded antidromically to stimulation of the pyramidal tract, indicating that their axons have the capacity to conduct impulses and are therefore likely to have developed some viable connections. The findings in this study provide insight into the structural characteristics of complexes involving heterocyclic bases and carboxylic acids, and demonstrate that X-ray crystallography and 15N solid-state NMR are truly complementary in elucidating hydrogen bonding interactions and the degree of proton transfer of these complexes.

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LSBs are artificial alleles created through molecular biology manipulations to be shorter or longer than alleles commonly seen in populations under investigation. Our aim was the investigation whether organic carbon or phosphorus is the restricting nutrient in specific water and determination of the impact of some treatment processes on MAP content. In the photosynthesis inhibition assay, agreement between experimental results and prediction was best for two-stage predictions considering the assigned modes of action. Special consideration is given to the mtDNA recognizing Toll-like receptor 9 and formyl peptide receptors.

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Characterization of organic low-dielectric-constant materials using optical spectroscopy. Monocyclic thiophenes as protein tyrosine phosphatase 1B inhibitors: capturing interactions with Asp48.

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Studies on lobar atrophy of the liver and compensatory hypertrophy caused by ligation of the hepatic duct in the rabbit In the present study, phylogenetic analysis of the structural subunits of hydrogenase syntons 1 and 2 showed a distinct clustering pattern between the proteins of Frankia strains that were isolated from different host plants and non-Frankia organisms.

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While increased fetuin-A levels positively correlated with vascular calcification in patients with diabetes and mild to moderate renal impairment, an inverse relationship was observed in dialysis patients. Being a lone working mother predicted a higher risk of heart disease, stroke, and smoking among American women, and smoking for European women.

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Interaction between coat protein and replication initiation protein of Mung bean yellow mosaic India virus might lead to control of viral DNA replication. Although multiple studies demonstrate protection by estrogen, in only a few instances is the issue of how the steroid confers protection known. Raloxifene significantly reduced mesangial expansion and fibronectin accumulation in db/db mice, but in contrast to 17beta-estradiol, it failed to affect body weight or hyperglycemia. Effect of end-tidal CO2 clamping on cerebrovascular function, oxygenation, and performance during 15-km time trial cycling in severe normobaric hypoxia: the role of cerebral O2 delivery. Good correlation between the magnitude of RAPD and intereye differences in mean deviation and estimated RGC counts suggests pupillometry may be useful for quantifying asymmetric damage in glaucoma.

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A reversal of preference was also observed: the CS associated with the smallest hypothetical shock was rated more positively than the CS associated with the smallest amount of hypothetical money. However, in strong contrast to other antibody isotypes, many details of the composition of the human IgE repertoire are poorly defined.

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Clinical, Psychosocial, and Demographic Factors Are Associated With Overweight and Obesity in Early Adolescent Girls With Type 1 Diabetes. Imaging and quantifying virus fluorescence signals on aquatic aggregates: a new method and its implication for aquatic microbial ecology. Council on Maternal and Child Health, National Association for Public Health Policy. Changes in isoelectric points of chromatin deoxyribonucleoproteins from Krebs II cells after infection with encephalomyocarditis virus.

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We demonstrate our method on several examples, and have implemented the framework in the open-source visualization system VTK. Weight, height, or length was measured on children and pregnant women.

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iNOS protein expression in these cells was detected by Western blot. Treatment of pain in bone metastases of prostatic carcinoma through unilateral left adrenalectomy

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Thermal dilution for measurement of cardiac output in the pulmonary artery in man in relation to choice of indicator volume and injection time. In homogenates of brain tissue of diabetic animals glutaminase does not differ markedly from that of control animals both in the presence and absence of activators (phosphate, aspartate, bicarbonate).