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Though efficacious, bosentan is less potent than the angiotensin converting enzyme (ACE) inhibitor, Enalapril, in patients with hypertension. In this study we investigated (i) the existence of the RAS components angiotensin converting enzyme (ACE) and angiotensin II receptors (AT(1) and AT(2)) in the rabbit cornea using in vitro and ex vivo models and (ii) the effect of Enalapril, an ACE inhibitor, to inhibit angiogenesis in rabbit cornea in vivo.

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Enalapril is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure can reduce the risk of strokes and heart attacks.

Enalapril is an angiotensin converting enzyme (ACE) inhibitor. It works by blocking a substance in the body that causes the blood vessels to tighten. As a result, enalapril relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart.

Enalapril is also used in combination with other medicines to treat congestive heart failure and cut down on the number of hospital visits for heart problems.

This medicine is available only with your doctor's prescription..

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(Present-day state of affairs, requirements and prospects for future development) Still, it is not known whether stem cells from the adult human brain retain the potential to mature into neurons that integrate and communicate in a network. Maternal biophysical characteristics, ultrasound parameters and placental analytes were compared between women with and without prior preeclampsia.

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First-principles study of structural and electronic properties of BxNyCz nanocones. The LCt50 was 5749 mg min m-3 and the subcutaneous LD50 1-2 mg kg-1.

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Palliative percutaneous drainage in malignant biliary obstruction. Behavior of the elastic tissue in some sclerosing and atrophizing skin diseases The clinical syndrome included fever and dyspnea (2 children), fever and abdominal pain (3), subcutaneous nodules or suppurative lymphadenitis (4).

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We show in situ assembly of a light emitter and photodetector based on individual nanostructures, demonstrating the potential application of the above technique in building prototype optoelectronic devices and selecting suitable nanostructures for device purposes. The kidney as an endocrine organ for the production of 1,25-dihydroxyvitamin D 3 , a calcium-mobilizing hormone. To examine the effects of colonization time, half of the trays were retrieved after two and the rest after five weeks.

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In this Review, we discuss how triggering of the prototypical CLRs leads to distinct pathogen-tailored TH cell responses and how we can harness our expanding knowledge for vaccine design and the treatment of inflammatory and malignant diseases. Nanocomposite of p-type conductive polymer/functionalized graphene oxide nanosheets as novel and hybrid electrodes for highly capacitive pseudocapacitors. A token reinforcement system for the reduction of institutionalized behavior in a chronic psychiatric ward is described. Behavior of transplanted adipose tissue of hereditarily obese mice. In this case report, we present a middle-aged man with a seeding metastasis of the cranial meningioma (after its removal) in the left thigh.

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Thus, in inflammatory joint disease TIMP-3 likely dampens the inflammatory response of TNF-alpha by reducing ADAM17 activity. Atorvastatin had no effect on the maximal postexercise variations in pHv and lactate but it significantly reduced the maximal increase in plasma potassium concentration after thumb adduction and handgrip exercise, the effects being only present at D90 on 10 mg/day but occurring as early as D30 with higher dosages. The temporomandibular joint and myofascial trigger areas in the dental diagnosis of pain.

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Experimental results show that the proposed method can successfully classify healthy controls and different ataxia types. When the stomach is unavailable for esophageal reconstruction due to previous gastrectomy or synchronous gastric cancer, a pedicled jejunum or colon, with or without vascular supercharge, has been the alternative. The review goes on to discuss how advances in analysis of spatiotemporal virus spread patterns within crops can help to enhance understanding of how virus epidemics develop and validate potentially useful virus control measures. Novel procedures and instrumentation are described for nuclear magnetic resonance (NMR) spectroscopy and imaging studies of live, in situ microbial films. 50 male rats were divided into 4 groups and raised for 8 weeks on diets containing white rice (WH), white rice and brown rice (WHBR), white rice and black rice (WHBL), brown rice and black rice (BRBL).

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Hair bearing skin strips were harvested from occipital area and sliced under magnification into grafts of various sizes. The purpose of this study was to determine the relationship between the CYP2D6 P34S polymorphism (C188T, rs1065852) and the efficacy of escitalopram treatment in Korean patients with MDD.

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Poly(ethylenimine)-Functionalized Monolithic Alumina Honeycomb Adsorbents for CO2 Capture from Air. The yield of systems for continuous and periodic injury surveillance in emergency care with emphasis on farm-work-related accidents. The use of fluorescent antibodies in the study of various infectious diseases. Steroid receptors and mammalian penile development: an unexpected role for progesterone receptor? Successful repair of a mitral valve aneurysm with cleft of anterior mitral leaflet in an adult.

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The purpose of this study is to determine whether long-term survival of post-valve replacement patients is affected by the presence of metabolic disease, and whether choice of tissue versus mechanical prosthesis impacts survival. The role of cytochrome P-450 in the N-oxidation of individual amines. Injuries can vary from simple minor penetrating skin wounds to major life-threatening soft and hard tissue damage with concurrent complex metabolic ramifications. Systematic review of emergency laparoscopic colorectal resection. However, due to the limited number of RCTs and poor methodology quality, we cannot reach a definitive conclusion, hence further large, rigorously designed trials are needed.

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A total of 161 patients with FE or microsurgical decompression underwent follow-up for 2 years. It was hypothesized that memory dysfunctions in animals after damage to the dorsal hippocampal CA3 field and to the hippocampus in general are determined by impaired transition of short-term into long-term memory. For the purpose of this article, we focused on the issues as they relate to the second prong of the definition of mental retardation, that is, adaptive behavior. Evaluation of (GTG)5-PCR for identification of Enterococcus spp. The resistance to diverse antibiotics and a higher ability to form biofilms found among the strains isolated from milk of women suffering mastitis may explain the chronic and/or recurrent nature of this infectious condition.

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Only drugs have so far been reported to cause this condition in the rat. Due to their small sizes, the nanoparticles can cross most of the biological barriers such as the blood vessels and the blood brain barrier, thus providing ubiquitous access to most tissues. Peritoneum of right upper belly was collected at 3 operation time points(the beginning, 2 hours, 4 hours). Advance awareness of the renal vascular anatomy, including variants of the left renal vein, is important for abdominal and renal surgery. Strategies for early identification, treatment and rehabilitation of impaired physicians are reviewed and suggestions for preventive action are given.

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The identification of a higher incidence of altered p53 expression in the SCC group raises the possibility of an association between schistosomiasis and alterations in p53 activation as an inciting event in colorectal cancer development. Given these well-established functions, it might be expected that mitochondrial dysfunction would give rise to a simple and predictable set of defects in all tissues. In this way we show that the binding of Pellino3 to IL-1 receptor-associated kinase 1 coincides with its ability to promote p38 MAPK activation.

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Activity of coumermycin against clinical isolates of staphylococci. A breast cancer diagnosis for women, regardless of age or caregiving status, presented an increased risk of depression at 3 and 12 months post-diagnosis.

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Biocompatibility of the chitin/gelatin membrane was assessed using human MG-63 osteoblast-like cells. However, comparisons between in vitro models and atherosclerotic tissue are difficult because ex vivo data are limited in their applicability to diseased peripheral vessels. Determination of monoamine oxidase and catechol orthomethyltransferase activity of the thrombocytes of healthy subjects of various age groups

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Routine nicotine replacement therapy is not indicated in smokers undergoing surgery for the purposes of managing nicotine withdrawal and stress but can modify some aspects of postoperative smoking behavior. Isolation of strains having abnormal alkaline phosphatase repressors Determination of in-vivo articular cartilage contact areas of human talocrural joint under weightbearing conditions. Ventricular myocytes were then subjected to metabolic inhibition and anoxia and isolated hearts to regional ischemia, followed by reperfusion to induce injury. Phase I data from healthy volunteers also suggest that inhibitors of Src prevent bone resorption.

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Outcomes have been reported for certain surgical procedures in professional athletes in the National Football League (NFL), but there is little information comparing the career effect of these procedures. We identify and describe here genes encoding putative chitin synthases in a variety of additional diatom genera, indicating that the ability to produce chitin is more widespread and likely plays a more central role in diatom biology than previously considered. Re: Predictors of Human Immunodeficiency Virus Knowledge among Jordanian Youths. Ubiquilin contains a UBL (ubiquitin-like) domain at the N-terminus and a UBA (ubiquitin-associated) domain at the C-terminus, separated by a central region containing Sti1-like repeats.

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Currently, it is believed that PPD with monoclonal T-cell population is more likely to progress to malignancy. Studies with animal models of type 2 diabetes have established that pharmacologic protection against oxidative stress ameliorates the severity of diabetes progression. Thank you for taking the time to listen to me: a reflection on clinical practice in the era of patient consumerism.

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Molecular and cellular effects of cis-9, trans-11-conjugated linoleic acid in enterocytes: effects on proliferation, differentiation, and gene expression. We describe the anatomic and physiological components involved in pain physiology, with the goal of providing readers with the background information needed to understand central pain control mechanisms. A regular CPC was established with pre-hospital transmitted real-time 12-lead electrocardiogram system for pre-hospital diagnosis of STEMI and enabled the STEMI patients to bypass the emergency room and directly treated in the catheter lab to shorten the D-to-B time.

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The acute myocardial infarction tissue showed obvious depletion of CTnI, there was no characterization of myocardial infarction in HE coloration. Here, we use high-throughput BCR sequencing to provide novel insight into B-cell dynamics following a primary course of hepatitis B vaccination. However, the actual motor system contribution to these time distortions is far from clear. Infectious bovine rhinoracheitis virus in bovine kidney cells: sequence of viral production, cellular changes, and localization of viral nucleic acid and protein.

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The dilysine motif KVKGS contained in UGT2 can be demonstrated to be responsible for the dual localization because: (1) disturbance of the signal via site specific mutation or C-terminal extension completely shifts the transporter to the Golgi, (2) transfer of the dilysine motif is sufficient to redistribute the Golgi CMP-sialic acid transporter to the ER, and (3) replacement of KVKGS by the strong ER retention signal KKNT is sufficient to completely retain UGT2 in the ER. The mechanism underlying abnormalities of lymphoid cell distribution which feature the autoimmune-prone NZB mice are not yet clear and further studies will be necessary before they can be characterized definitively. The pathophysiological morphology of the pigment epithelium and its importance for retinal structures and functions. Probably, the terminal Schwann cells together with the axon terminals regulate mechanotransduction in the periodontal endings.

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Utilization of the method of local thermodilution in the clinical estimation of blood circulation in the liver PTPN11 gene mutations were described in several individuals with this phenotype, and it is recently considered as a variant phenotype of NS. Nickel binding properties of Helicobacter pylori UreF, an accessory protein in the nickel-based activation of urease. Morphological changes in human schistosomiasis and certain analogies in ancient Egyptian sculpture.

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A central question, therefore, is how global transcription is coordinated in the genome. The relationship between suicidal ideation and symptoms of depression in Japanese workers: a cross-sectional study. Nine neoplastic nodules were examined and found to be resistant to the CCl4 induced necrosis, although cells in the nodules were actively dividing at the same rate as in the regenerating surrounding normal liver parenchyma. Combination of prolapse of folds of the gastric mucosa into the duodenal bulb and ulcer of the bulb The oculouretrosynovial syndrome (Fiessinger-Leroy-Reiter syndrome)

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In this study the chromosomal localization and the expression of human cytochrome P1-450 gene were determined in phytohemagglutinin-stimulated lymphocytes. A batch test on bacterial adhesion onto the sheets clarified that the DEA-containing sheet (DEA sheet) exhibited an adhesion rate constant, k, significantly greater than those of other types of sheet.

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Single polarity indexes, such as the Hildebrand solubility parameter or the partition coefficient (PC), do not fit well the overall experimental data. Behavior of blood and tissular fluid exchange in relation to work The aim is to investigate the photoinduced change in the charge distribution with 50-fs time resolution by probing the effects on the tryptophan absorption bands. The addition of an extra nitrogen source in the form of NH4Cl at pH 5.5 did not result in any improvement in fermentability that was comparable to NH4OH treatments at alkaline conditions.

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An active protein kinase A (PKA) is involved in meiotic arrest of rat growing oocytes. Reminiscences about Kotarbinski, physician and concentration camp prisoner The performance of laboratory scale methanol-degrading biofilters packed with lava rock was checked during almost 1 yr under different conditions. The histopathological changes on internal anal sphincter (IAS) have been reported, but ultrastructure changes of external anal sphincter (EAS) are unknown.

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Recent evidence supports a model whereby CaSR-mediated activation of integrins promotes cellular migration. Migration of Strongyloides papillosus in lambs and accompanying pathologic changes following percutaneous infection. The effect of vinblastine and demecolcine on circulating megakaryocytes in adult rats. In this article, we describe another case of heel neuroma in an otherwise healthy patient with a history of chronic plantar heel pain that was unresponsive to a wide array of nonsurgical treatments. The binding affinity of three VHHs, ZFR-1, ZFR-2, and ZFR-5, ranged from 2.5 to 80 nM, and among them, ZFR-5, which was selected for proliferation assay, significantly inhibited the endothelial cell growth in a dose-dependent manner.

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We conclude that the ability to measure methylmalonic acid in human serum will be useful in studies designed to determine the incidence of cobalamin deficiency in various patient populations. Adult rats deprived at perinatal age and then rehabilitated on balanced chow were treated with a multiple amphetamine (AMPH) schedule (2 mg/kg/48 hr) and submitted, on days of injections, to an open-field test.

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We show that the resistivity exhibits a scaling behavior near the percolation threshold found from analysis of the compressibility. Fate of human fertilized eggs during prenatal life: present status of knowledge. The results of this study provide a pharmacological basis for the use of C. Molecular evolution of the major chemosensory gene families in insects. Dynamic light scattering studies indicate that the size distribution of the nanoforms widens in presence of the protein.

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To establish a dog model of testis autotransplantation with a modified technique. The scanning laser ophthalmoscope images at 488 nm and 514 nm were rated superior to images at 633 nm and 780 nm, the color fundus photograph, and the red-free fundus photograph. Cannabinoid tolerance and dependence: a review of studies in laboratory animals. Health plan members 18 years of age and older, not receiving chemotherapy, who had received at least 1 statin prescription between January 1, 1997, and December 31, 2001 were eligible. bovis cercariae, which did not cause significant liver damage, did not protect significantly against challenge with F.

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The velocity of this finger joint opening varied with the speed of the throw. There are two canSNP subgroups found in Liaoning, A.Br.001/002 and A.Br.Ames, and a total of six MLVA 15 genotypes and five SNR genotypes were observed. Contingency sessions offered a choice between two alternative fixed-ratio components, in the form of a choice between the two levers. This study was designed for clinical and laboratory evaluation of intestinal obstruction (IO) in buffaloes (Bubalus bubalis) with special emphasis on the diagnostic value of ultrasonographic findings. Moreover, MET at 20 degrees C, METT and gonad lipids were significantly induced at the polluted sites.

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Transient anosognosia associated with thalamotomy: is it caused by proprioceptive loss? Electrolyte-free liquid formula diet: metabolic effects and possible clinical uses. Introduction to the Canadian 24-Hour Movement Guidelines for Children and Youth: An Integration of Physical Activity, Sedentary Behaviour, and Sleep. For that, a set of presynaptic neurons is activated in a precisely timed sequence through focal photolytic release of caged glutamate with the help of a fast laser scanning system.

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To confirm the effectiveness of loratadine for relieving pruritus in atopic dermatitis, we examined the effect of this drug using animal models of atopic dermatitis associated pruritus in ICR and hairless mice. Infections are common after intracerebral hemorrhage, but little is known about the risk of serious infection requiring readmission after hospital discharge.

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An evaluation of para-aortic and pelvic lymph node metastases in patients with endometrial carcinoma Trypanosome telomeres are protected by a homologue of mammalian TRF2.

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The treatment of epilepsy in pregnancy: The neurodevelopmental risks associated with exposure to antiepileptic drugs. A correlation was established between the pattern of motor and tonic disorders and the pattern of catecholamine secretion during multi-stage duodenal exploration.

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Chi2 and logistic regression measured associations with the prescription of warfarin. Adaptation to conditions of limited oxygen availability (hypoxia) is a critical determinant of cell and tissue viability in several physiological and pathophysiological conditions. Human adult pluripotent stem cells, stem cells of embryonic origin and induced pluripotent stem cells (iPS) provide cellular sources for new promising regenerative medicine approaches. This connection through the ventral wall prevents normal egress of the gut into the umbilical cord during the second month of development and acts as the egress point for the gut resulting in gastroschisis.

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These findings indicate that BLA modulation of memory consolidation requires concurrent DA receptor activation in the NAc shell but not the caditar 400 mg indicaciones tonval 40 core. Most of the observed bands were not exclusive to one treatment but could be recognized in chromosomes prepared by several methods. Present status of treatment of immunodeficiency with special reference to cellular immunologic deficiency Five new alpha-methylene-gamma-lactone-bearing cembranoid diterpenes, sinularolides A-E (1-5), along with 10 known cembranoids, were isolated from the soft coral Sinularia gibberosa.

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Using time-sampled EMA, we assessed the sierra foothills avas are best known for franklin the proportion of the day spent in positive and negative social interactions. There is no expression of this transgene in the urothelium or in the kidney. Measuring the acoustic impedance changes of the batter its compressibility and density can be monitored.

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In addition, two freeze-dried commercially available preparations were tested. The observations suggest that trace metals are not immediately bound in an insoluble, inert form when they are in contact with sulphide. In particular, we will examine the optimal physicochemical properties for oral absorption based on solubility, permeability, and a few easily computed parameters. Differential early rearing affects response to overfeeding in B6D2F2 mice. Our data suggest that, finara tab although COX-2 is the prominent isoform, COX-1 activity may significantly contribute to excitotoxicity, particularly when considering the amount of lipid peroxidation associated with its catalytic cycle.

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We describe here an assay for assessing the relative cell permeability of synthetic molecules in the context of steroid fusions that is capable of high throughput and can be used in any transfectable cell line. Achieving high and reliable levels of expression ezetrol missed dose of metformin is essential for biotechnological application of transgene technology.

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Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease. Laparoscopic placement of zyllt 75 mg pret a feeding jejunostomy is the most recently described enteric access route. Nine of 10 beagle dogs with bronchopleural fistula were treated successfully by plug occlusion. We found here that patients diagnosed with sepsis, in contrast to healthy individuals, had substantial levels of soluble TLT-1 (sTLT-1) in their plasma that correlated with the presence of disseminated intravascular coagulation.

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Two package boilers: virolex 200 mg tabletta an investment with an annual return of 36 percent. A new approach for calculating the relative risk level of pesticides. The relationship between the supply of fast-food chains and cardiovascular outcomes. These results demonstrate for the first time that the anti-inflammatory actions mediated by gliotoxin include HO-1 induction and the subsequent blockade of NF-kappaB-dependent signaling pathways in vitro and in vivo.

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In vitro studies of pure Schwann cells have shown that these cells can respond directly to mechanical stimuli by downregulating myelin proteins and proliferating. Patients were categorized by treatment group, and linear regression was used to calculate trends in treatment and predictors of treatment group. The recovered lysozyme exhibited an activity equivalent to the native lysozyme and its secondary structure was also unchanged. The difference of the 6 CA16 strains analyzed showed that the most prominent strain was the A genotype, and the most close strains were bactrim dosing renal failure the B1 gene subtype, particularly the B1b gene subtype.

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Spindle-cell sarcoma of the popliteal fossa mimicking a benign vascular lesion. Its antiangiogenic effect is used in ophthalmology as an off-label treatment for retinal disease. However, over the past few years the number of novel Burkholderia visram drugs limited clothing species that exhibit plant-beneficial properties and are normally not isolated from infected patients has increased tremendously.

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Detection and quantitation of a ring-hydroxylated metabolite of the antidepressant drug tranylcypromine. The diminution appears to be due to the presence of inhibitors that do not inhibit clarithromycin 500 mg and amoxicillin 500mg dosage the base specific enzymes to the same extent. An enzymic reduction system for metmyoglobin and methemoglobin, and its application to functional studies of oxygen carriers.